WebJan 15, 2024 · Since its discovery in 1908, phenytoin has become one of the most well-studied anticonvulsants. With an average monthly cost of $30, it has also become one of the most widely used anticonvulsants, listed on the World Health Organization’s List of Essential Medicines. However, with its narrow therapeutic index and its pervasive daily use, … WebApr 5, 2024 · In the present work, a new phenytoin derivative, 3-allyl-5,5-diphenylimidazolidine-2,4-dione, formulated as C 18 H 16 N 2 O 2 was synthesized and its …
Structure of phenytoin. Download Scientific Diagram
WebSep 4, 2024 · Fosphenytoin is a medication used to manage seizures (treatment of generalized tonic-clonic status epilepticus, focal [partial] onset seizures, or generalized … Common side effects include nausea, stomach pain, loss of appetite, poor coordination, increased hair growth, and enlargement of the gums. Potentially serious side effects include sleepiness, self harm, liver problems, bone marrow suppression, low blood pressure, and toxic epidermal necrolysis. There is evidence that use during pregnancy results in abnormalities in the baby. Its use appears to be safe during breastfeeding. Alcohol may interfere with the medication's effects. c 抽象类
Structure of phenytoin. Download Scientific Diagram
WebPhenytoin is extensively metabolized and is first transformed into a reactive arene oxide intermediate. 12 It is thought that this reactive intermediate is responsible for many … WebFeb 3, 2024 · phenytoin ). Anticonvulsants are also used for pain management (e.g., carbamazepine or gabapentin ) and as mood stabilizers in bipolar disorders ( valproate ). For more information on the treatment of generalized seizures , see treatment of epileptic seizures. Overview WebSep 19, 2024 · Phenytoin is extensively bound to plasma proteins and is prone to competitive displacement. Phenytoin is metabolized by hepatic cytochrome P450 … c 指定設備導入事業 補助金額