WebFeb 9, 2024 · BackgroundSolid predominant adenocarcinoma (SPA) has been reported to be a subtype with poor prognosis and unsatisfactory response to chemotherapy and targeted therapy in lung adenocarcinoma (LUAD). However, the underlying mechanisms remain largely unknown and the suitability of immunotherapy for SPA has not been … WebAug 31, 2024 · Validation of subtypes and the correlation between subtypes and clinical data in LUAD. Among the DEGs and corresponding genes of the methylation sites, the …
Cancers Free Full-Text PATZ1 in Non-Small Cell Lung …
WebApr 7, 2024 · Lung cancer is the most common cause of cancer deaths worldwide, and lung adenocarcinoma (LUAD) is the most common histological subtype. However, the prognostic and predictive outcomes differ because of this cancer type heterogeneity. LUAD subtypes … WebCompilation of TCGA molecular subtypes - Bioconductor gunfighter terminus
Frontiers Immune Subtypes in LUAD Identify Novel Tumor ...
WebApr 6, 2024 · On the other hand, nuclear expression of PATZ1 is negatively associated with the LUAD subtype, and Patz1-knockout mice develop lung adenocarcinomas. Consistently, overexpression of PATZ1 in LUAD cells inhibits cell proliferation, migration, and invasion, suggesting a tumor suppressor role of this gene in NSCLC, likely by counteracting the ... WebJun 3, 2024 · Lung adenocarcinoma (LUAD) is one of the most common histological subtypes of lung cancer. The aim of this study was to construct consensus clusters based on multi-omics data and multiple algorithms. In order to identify specific molecular characteristics and facilitate the use of precision medicine on patients we used gene … WebAug 31, 2024 · Validation of subtypes and the correlation between subtypes and clinical data in LUAD. Among the DEGs and corresponding genes of the methylation sites, the validation group (i.e., the GSE32863 data set) only comprised 298 genes and 2 methylation sites. Next, we classified the 58 samples into 2 subtypes using the NMF method (see … gun that looks like a phone case