WebFind a CVS Pharmacy location near you in Boston, MA. Look up store hours, driving directions, services, amenities, and more for pharmacies in Boston, MA WebJul 3, 2015 · The objective of this study was to determine the efficacy of a novel, highly potent, orally-bioavailable c-MET inhibitor, INC280, in blocking cell phenotypes important in ovarian cancer metastasis. Using in vitro and ex vivo models, we demonstrate that INC280 inhibits HGF-induced c-MET, and reduces downstream signalling.
indipendente: INC280, プラセボの臨床試験-臨床試験登録-ICH GCP
WebJul 3, 2015 · Scientific Reports - INC280, an orally available small molecule inhibitor of c-MET, reduces migration and adhesion in ovarian cancer cell models WebCapmatinib (INCB28060, INC280, NVP-INC280) is a novel, ATP-competitive inhibitor of c-MET with IC50 of 0.13 nM in a cell-free assay, inactive against RONβ, as well as EGFR and HER-3. Capmatinib (INCB28060) inhibits Wnt/β-catenin and EMT signaling pathways and induces apoptosis in diffuse gastric cancer positive for c-MET amplification. Phase 1. northampton jailed
2024年12月現在 消化管・腫瘍内科
WebApr 10, 2015 · Study Description. A phase II study to evaluate antitumor activity of oral cMET inhibitor INC280 in adult patients with EGFR wild-type, advanced non-small cell lung … WebJul 19, 2024 · 概要 一般名 テポチニブ 商品名 テプミトコ 治験薬コード INC280 一般名英語表記 Tepotinib 商品名英語表記 TEPMETKO 種類 抗悪性腫瘍剤(MET阻害剤) 投与経路 … WebNov 6, 2024 · Patients may also be assigned to EGF816 + INC280 or EGF816 + gefitinib in dose expansion. Efficacy assessments will be performed at baseline and every 2 cycles during treatment. Study Design. Go to Top of Page Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More … how to repair small appliances mobile alabama