WebModerately emetogenic treatment—the taxanes, doxorubicin hydrochloride, intermediate and low doses of cyclophosphamide, mitoxantrone, and high doses of methotrexate (0.1– 1.2 g/m 2). Highly emetogenic treatment—cisplatin, dacarbazine, and high doses of cyclophosphamide. WebNov 1, 2024 · The pathophysiological bases for ototoxicity or neurotoxicity are not yet fully understood, although there is evidence that the formation of reactive oxygen and nitric …
Prevention of cisplatin-induced ototoxicity in children and …
WebSep 21, 2016 · Cisplatin is the most ototoxic drug known, and a mean ototoxicity incidence of 33% has been reported when patients received a single dose of 50 mg/m 2 of cisplatin. 1 Investigations using audiometric techniques revealed a frequency of cisplatin-induced ototoxicity of approximately 20% to 40% after a high cumulative dose of … WebOur purpose was to determine the risk of ototoxicity in breast cancer patients receiving a myeloablative regimen consisting of cyclophosphamide 6000 mg/m2, thiotepa 500 … fnf tom\\u0027s basement show
Ototoxicity after high-dose chemotherapy with …
WebCytoxan: 1 person, 5.88% Adriamycin Rdf: 1 person, 5.88% Common side effects people have besides Ototoxicity *: Vestibular Disorder (disorders of the body's balance (vestibular) system in the inner ear): 5 people, 29.41% Deafness Neurosensory: 3 people, 17.65% Hearing Loss: 2 people, 11.76% Deafness Bilateral: 2 people, 11.76% WebDrugs may cause hearing loss, dysequilibrium, and/or tinnitus. Common drugs include aminoglycosides, platinum-containing chemotherapy drugs, and high-dose salicylates. Symptoms may be transient or permanent. Using the lowest possible dose of aminoglycosides and measuring drug levels during treatment may prevent hearing loss … WebSep 15, 2024 · Mabs, the main cause of type 2 damage, are widely used in the management of many types of cancer. Chemotherapy agents that can cause reversible cardiotoxicity are trastuzumab, bevacizumab, lapatinib, and sunitinib. These agents also may cause hypertension. A decrease in vascular endothelial growth factor (VEGF) results in a … greenville sc to hiawassee ga