Cisplatin interactions

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August undefined, 2024

WebFeb 1, 2024 · Cisplatin may cause serious kidney problems. Tell you doctor right away if you have blood in urine, change in frequency of urination or amount of urine, difficulty in … WebAug 19, 2005 · Cisplatin is a widely used anti-tumor agent for the treatment of testicular and ovarian cancers. Carboplatin is used extensively for small cell, non small cell lung cancer and ovarian cancer. ... (FT-IR), and nuclear magnetic resonance (NMR) studies of cisplatin-protein interactions have provided only low-resolution information on the mechanism ...

Cisplatin Interactions Checker - Drugs.com

WebTypes of interactions: Beneficial Adverse Check Replenish Depleted Nutrients Magnesium and Potassium Calcium Lactobacillus GG N-Acetyl Cysteine Sodium Spleen Peptide … Web1 day ago · Two NPC cell lines, with distinct ENOX2 expression, were used in a co-culture platform to study tumor-immune interactions between cancer cells/spheroids and T-cells. The effect of cisplatin treatment with ENOX2 inhibition by idronoxil (IDX) were tested in vitro and in vivo. Multi-parametric flow cytometry was used to characterize T-cell ... raymond akpederi

Cisplatin Injection: Uses & Side Effects Cleveland Clinic

WebSep 18, 2024 · CIsplatin has several black box warnings, including nephrotoxicity, peripheral neuropathy, severe nausea and vomiting, and myelosupression. Gastrointestinal toxicity - Nausea and vomiting are dose-related side effects that can be severe and lead to metabolic derangements; this can persist for up to 1 week after administration. Webblood test abnormalities (low magnesium, low calcium, low potassium, increases in liver function, increases in uric acid) Less common cisplatin side effects (10% - 30% of patients) include (8): loss of appetite, changes in taste. neuropathy (changes in or damage to nerve function, often in the hands and feet) numbness. WebIn general, combination of cisplatin with an antimetabolite, taxane, or topoisomerase inhibitor, can result in a modulation of platinum pharmacology on the DNA, for example, … simplicity 9330

Cisplatin - NCI - National Cancer Institute

Cisplatin - Wikipedia

WebThe information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is ... WebMedication Interactions Full Drug Information Search Drugs Related Drugs Common Searches Adderall Celexa Cipro Cymbalta Flexeril Hydrocodone Prilosec Prozac … simplicity 9334 reviewWebNo interactions were found between cisplatin and Cyclafem 7/7/7. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider. cisplatin A total of 410 drugs are known to interact with cisplatin . Cisplatin is in the drug class alkylating agents . Cisplatin is used to treat the following conditions: simplicity 9332

"WebApr 24, 2015 · The clinical manifestations of cisplatin nephrotoxicity are a decreased glomerular filtration rate, increased serum creatinine level, reduced serum magnesium and potassium levels (Pabla and Dong, 2008), and the development of proteinuria of tubular and glomerular origin (Daugaard, 1990). " - Cisplatin interactions

Cisplatin interactions

Cisplatin Side Effects: Common, Severe, Long Term - Drugs.com

Web1152 rows · Jun 13, 2005 · Cisplatin may increase the bradycardic activities of Nebivolol. Nedaplatin: Cisplatin may ... http://referentiels-aristot.com/wp-content/uploads/08_Soins-de-Support_2024_prise-en-charge-nutritionnelle-moyen-prise-en-charge.pdf

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WebApr 19, 2024 · fast heartbeats, lightheadedness, wheezing, severe or ongoing nausea and vomiting, vision problems, pain behind your eyes, pain, redness, swelling, or skin changes where the injection was given, dizziness, pale lips or fingernail beds, shortness of breath, little or no urination, swelling in your feet or ankles, tiredness, fatigue, fever, WebJan 11, 2024 · Cisplatin interaction with the serine group of phospholipids (e.g., PS) has also been extensively studied. Using electron microscopy and X-ray diffraction, it was observed that cisplatin inserted into the inner monolayer of human erythrocytes and induced stomatocytic shape changes ( Suwalsky et al., 2000 ), most likely due to the …

WebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in … WebFeb 26, 2024 · hearing problems; kidney problems; numbness or tingling; nausea, vomiting; or. bone marrow suppression. This is not a complete list of side effects and …

Web4 hours ago · Moreover, in cisplatin-induced renal injury models, they also reduced serum blood urea nitrogen (BUN) and creatinine levels to different degrees, the best of which was 6-methylflavone. The pharmacophore model clarified that the aromatic ring, hydrogen bond acceptors, and hydrogen bond donors might play a vital role in the inhibitory effect of ... Webcisplatin, selinexor. unspecified interaction mechanism. Avoid or Use Alternate Drug. Patients treated with selinexor may experience neurological toxicities. Avoid taking selinexor with other...

WebCisplatin is a chemotherapy medication used to treat a number of cancers. These include testicular cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, …

WebMar 30, 2024 · The following have been found to interfere with the effectiveness of cisplatin: Beef Capers Caviar Grapefruit and … raymonda khouryWebMay 1, 2005 · A clear synergistic interaction between cisplatin and IR is observed in cells proficient in nonhomologous end joining (NHEJ) catalyzed repair of DNA double-strand breaks (DSB). In contrast, no interaction between cisplatin and IR is … raymond akers iowaWebFeb 1, 2024 · Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this medicine. simplicity 9328Webwith solid tumors receiving cisplatin-based highly emetogenic chemotherapy (HEC). Support Care Cancer. 2015 Oct;23(10):2917–23. ... Aprepitant: drug-drug interactions in perspective. Ann Oncol. 2010 Dec;21(12):2316–23. 20. Zhang L, Lu S, Feng J, Dechaphunkul A, Chang J, Wang D, et al. A Randomized Phase 3 Study Evaluating the … simplicity 9336WebCisplatin (DDP) is a common therapeutic option for non-small cell lung carcinoma (NSCLC). However, some patients fail to respond to the DDP chemotherapy. Therefore, identifying novel biomarkers to improve the diagnosis and treatment of NSCLC is important. ... USP14-EGFR interaction was confirmed using co-immunoprecipitation (Figure 3A ... raymond akinsWebCisplatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: nausea vomiting diarrhea hair loss loss in ability to taste food hiccups dry mouth, dark urine, decreased sweating, dry skin, and other signs of dehydration Some side effects can be serious. raymond a. kresgeWebThere are 7 disease interactions with cisplatin. Infections Hearing loss Myelosuppression Peripheral neuropathy Renal dysfunction Hemolytic anemia Ocular toxicity Major … raymond a kimble