Cisplatin hplc
WebCisplatin, cis-diamminedichlorido-platinum(II), is an important therapeutic tool in the struggle against different tumors, yet it is plagued with the emergence of resistance mechanisms after repeated WebGemcitabine (Gem) and cisplatin (Cis) are currently being used for lung cancer treatment, but they are highly toxic in high dosages. This research aimed to develop a niosome formulation...
Cisplatin hplc
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WebAug 19, 2005 · Cisplatin is a widely used anti-tumor agent for the treatment of testicular and ovarian cancers. Carboplatin is used extensively for small cell, non small cell lung cancer … WebNov 1, 2005 · Although a number of methods have been described for the determination of cisplatin in human fluids by high-performance liquid chromatography (HPLC), there are …
WebNov 1, 2008 · We found that AGT is readily cross-linked to DNA in the presence of cisplatin. HPLC-ESI⁺-MS/MS sequencing of tryptic peptides originating from dG-Pt-AGT complexes revealed that the cross-linking ... WebFeb 28, 2024 · Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels. Xiaoxu Zhao 1 Department of General Surgery, ... HPLC analysis detected high concentrations of cisplatin in tumors after combined therapy, both of which indicated that the delivery efficacy of cisplatin was …
WebCisplatin was the first of the platinum-based chemotherapeutic agents and therefore has been extensively studied as an antitumor agent since the late 1960s. Because this agent … WebMar 11, 2024 · Cisplatin (CDDP), a platinum-based drug, is the most potent anti-cancer agent and is widely used for cancer treatment [ 1 ]. In particular, it plays crucial roles in …
Webneeded. As cisplatin is a metal-based molecule, historical analyses include phosphorescence, high-performance liquid chromatography with ultraviolet visible …
WebCisplatin was the first of the platinum-based chemotherapeutic agents and therefore has been extensively studied as an antitumor agent since the late 1960s. Because this agent forms several DNA adducts, a highly sensitive and specific quantitative assay is needed to correlate the molecular dose of individual adducts with the effects of treatment. chubb claim formWebA high-performance liquid chromatographic (HPLC) method is described for the determination of residual levels of cisplatin from extracts of surfaces with very low … desert warrior anthony mackieWebFeb 26, 2015 · Cisplatin and apigenin were purchased from Sigma-Aldrich (St. Louis, MO, USA). All other reagents were of analytical grade or HPLC grade, and were obtained from DIMA Technology, Inc. (Richmond Hill, GA, USA). Analytical procedures. Cisplatin was separated by HPLC using a Symmetry C18 column (50×2.1 mm; Waters Corporation, … chubb city homeWebcisplatin-plus lipoic acid (50 and 100 mg/kg)-treated rats, renal GSH-peroxidase activity significantly increased as compared to cisplatin alone (P ,0.01 and P 0.01) (fig. 3). The renal GSH-peroxidase activity in lipoic acid (100 mg/ kg) alone treated group was 247.02”15.52 mmoles NADPH oxidized/min./mg protein which was close to control value. desert waves commercial brokershttp://www.ijsit.com/admin/ijsit_files/ijsit_1.1.5.pdf desert way oil field \\u0026 gas estWebJul 13, 2015 · Cisplatin is one of the first-choice drugs for the treatment of many cancers but it is not without its disadvantages, principally toxicity to the liver, kidney, brain and gastrointestinal tract, the initiation of hearing loss, and suppression of bone marrow. desert way pipes \\u0026 fittings tradingWebKey Words:Oxaliplatin, RP-HPLC, UV detection, recovery, precise, 240nm INTRODUCTION Oxaliplatin is a platinum-based antineoplastic agent that is used in cancer chemotherapy. oxaliplatin is the platinum-containing complex similar to cisplatin. This agent was recently approved for use as a second line therapy in metastatic colorectal cancer. desert washroom cleaner