Circrhot1

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August undefined, 2024

WebMar 29, 2024 · circRHOT1 was overexpressed in pancreatic cancer and that this circRHOT1 was predominantly located in the cytoplasm. Reducing the circRHOT1 … WebBackground: Lung cancer is a common malignant tumor around the world. Propofol has been found to play an anti-tumor role. Therefore, the purpose of this study is to clarify the role and underlying molecular mechanisms of Propofol in …

Circular RNA RHOT1 promotes progression and inhibits …

WebNov 28, 2024 · Furthermore, overexpression of STAT3 and the use of a miR-106a-5p inhibitor reversed BC progression that was mediated by circRHOT1 knockdown and also increased the levels of ROS, iron, and Fe 2+. Taken together, this study suggests that circRHOT1 promotes BC progression via the miR-106a-5p/STAT3 axis . can be classified into three categories

circRHOT1 knockout suppresses HCC cell proliferation, migration …

WebNoteworthy, circRNAs mainly function through sponging microRNA (miRNA) or directly with targeted proteins. 7 For example, circRHOT1 epigenetically regulates lung cancer progression via recruiting KAT5. 15 Importantly, the previous studies have identified the critical function of circRNAs in the regulation of MI progression, including circTtc3 ... Web(a) circRHOT1 level in BC cell lines detected by qRT-PCR. (b, c) circRHOT1 and RHOT1 mRNA expression measured by qRT-PCR in HT-1376 (b) and HTB9 (c) cells treated with … WebJul 22, 2024 · CircRHOT1 is overexpressed and affects the biological function of pancreatic cancer cells. A, Relative expression of circRHOT1 in PDAC cells and human pancreatic … fishing classic wow guide

RNA sequencing reveals the expression profiles of circRNA and ...

ZNF652-Induced circRHOT1 Promotes SMAD5 Expression to …

WebThe circRHOT1 knockdown notably increased the levels of reactive oxygen species (ROS), iron, and Fe 2+ in breast cancer cells. Mechanically, circRHOT1 was able to sponge microRNA-106a-5p (miR-106a-5p) and inhibited ferroptosis by down-regulating miR-106a-5p in breast cancer cells. Besides, miR-106a-5p induced ferroptosis by targeting signal ... WebHCC cells were infected with CRISPR/Cas Lentivirus containging circRHOT1-sgRNAs. circRHOT1-deficient HCC cells were screened out. Growth protocol HCC cells were cultured in DMEM medium supplemented with 20 % FBS, 2 mM glutamine, 1 mM pyruvate, 10 mM HEPES, 100 units/mL penicillin/streptomycin, 0.1 mg/mL gentamicin, and 2 g/L … fishing classic wow 150 225WebKnockdown of circRHOT1 expression significantly inhibited proliferation as well as invasion, and it promoted apoptosis of pancreatic cancer cells via the regulation of E2F3 through the targeting of miR-125a-3p.Conclusion: Taken together, our results demonstrated that circRHOT1 plays critical roles in regulating the biological functions of … can be clearly observed

"WebCircRHOT1 represses autophagy and in the OA rat model. (a)–(e) The OA rat model was constructed by receiving ACLT, and the OA rats were treated with circRHOT1 shRNA. (a) The expression of... " - Circrhot1

Circrhot1

WebMar 4, 2024 · For instance, Wang et al. found that the high expression of circRHOT1 was associated with poor prognosis of hepatocellular carcinoma (HCC), and confirmed that circRHOT1 promoted malignant progression of tumors , Liang et al. discovered a new circRNA from breast cancer tissues, named circBMPR2, and identified its role in … WebMar 15, 2024 · Several circRNAs have been identified as key modulators in HCC progression, including cSMARCA5, 12 circTRIM33-12, 13 and circRHOT1. 14 In addition, a growing number of studies have focused on the competitive inhibitory effect …

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Web(a) circRHOT1 level in BC cell lines detected by qRT-PCR. (b, c) circRHOT1 and RHOT1 mRNA expression measured by qRT-PCR in HT-1376 (b) and HTB9 (c) cells treated with RNase R or mock. WebcircRHOT1 and TIP60. RNA-sequencing method was used to analyze the downstream target gene of circRHOT1. Results: We identified circRHOT1 (hsa_circRNA_102034) as …

WebAug 16, 2024 · Novel therapeutic strategies for BC clinical intervention are therefore urgently needed now more than ever. circRHOT1 is a newly identified circRNA that plays a … WebJun 11, 2024 · Circular RNA circRHOT1 promotes hepatocellular carcinoma progression by initiation of NR2F6 expression Mol. Canc. (2024) D.H. Bach et al. Circular RNAs in cancer Mol. Ther. Nucleic Acids (2024) Z. Peng The long noncoding RNA LINC00312 induces lung adenocarcinoma migration and vasculogenic mimicry through directly binding YBX1 Mol. …

WebFigure 1. CircRHOT1 is enhanced in clinical NSCLC samples and NSCLC cell lines. (A) The expression of circRHOT1 was analyzed by qPCR in clinical NSCLC tissues (n = 60) and … WebAug 12, 2024 · Circular RNA circRHOT1 promotes hepatocellular carcinoma progression by initiation of NR2F6 expression Abstract Background: Increasing evidence has revealed a close relationship between...

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WebJun 1, 2024 · CircRHOT1 is a recently spotted circular RNA that is upregulated in several cancers, mainly in hepatocellular carcinoma and pancreatic cancer. ( Zhang et al., 2024, Ling et al., 2024 ), and participates in the regulation of tumor cell proliferation and death ( Ling et al., 2024, Qu et al., 2024 ). Yet, the role of circRHOT1 in asthma is not clear. fishing classes for kidsWebJul 19, 2024 · CircRHOT1, linear RHOT1 and 18S probes for northern blotting were achieved using the Biotin RNA labeling mix (Roche). The RNA samples were separated … can be clearly seenWebDec 9, 2024 · Novel therapeutic strategies for BC clinical intervention are therefore urgently needed now more than ever. circRHOT1 is a newly identified circRNA that plays a crucial role in multiple types of tumorigeneses. However, it remains unclear whether circRHOT1 plays a functional role in BC progression. can be combativeWebCircular RNAs (circRNAs) have been identified as a sort of critical regulator in cancer progression. In this study, we identities the epigenetic regulation function of circular RNA … fishing cleaning table with sinkWebDownload scientific diagram circRHOT1 knockout suppresses HCC cell proliferation, migration and invasion but promotes apoptosis. a The expression of circRHOT1 was analyzed by qRT-PCR in ... fishing clawWebCircRHOT1 enhances CCND1 expression by sponging miR-142-5p to inhibit chondrocyte autophagy and promote chondrocyte proliferation in OA [143]. Circ_0005526 promotes IL-1β-induced chondrocyte ... can be closed outWebAug 18, 2024 · Circular RNAs (circRNAs) have been identified as a sort of critical regulator in cancer progression. In this study, we identities the epigenetic regulation function of circular RNA circRHOT1 in promoting NSCLC cell proliferation. We found that circRHOT1 were elevated in… View PDF Save to Library Create Alert Cite Figures from this paper … fishing clearwater lake mn